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Purple Biotech Ltd., a clinical-stage company, focuses on developing therapies to overcome tumor immune evasion and drug resistance for cancer patients in the United States. Its oncology pipeline includes CM24, a humanized monoclonal antibody that blocks the interactions of carcinoembryonic antigen related cell adhesion molecule 1 as a combination therapy with anti-PD-1 checkpoint inhibitors, which is in Phase 2 clinical trial for the treatment of pancreatic ductal adenocarcinoma; NT219, a small molecule that targets and inhibits insulin receptor substrate 1 and 2, and signal transducer and activator of transcription, which is in Phase 1/2 clinical trials for the treatment recurrent and/or metastatic squamous cell carcinoma of the head and neck cancer or colorectal adenocarcinoma; and IM1240, a multi-valent antibody designed to activate anti-tumoral immune response against 5T4-positive tumors, which is in preclinical stage. The company has collaboration agreement with Bristol Myers Squibb Company to evaluate the combination of CM24 with the PD-1 inhibitor nivolumab in addition to chemotherapy. The company was formerly known as Kitov Pharma Ltd and changed its name to Purple Biotech Ltd. in December 2020. The company is headquartered in Rehovot, Israel.
Name | Age | Since | Title |
---|---|---|---|
Sunil Sharma | - | 2023 | Member of Scientific Advisory Board |
Robert E. Gagnon | 49 | 2021 | Independent Director |
Ori Hershkovitz | 48 | 2021 | Independent Director |
Steven Maron | - | 2023 | Member of Scientific Advisory Board |
Scott Faucett | - | 2014 | Member of Scientific Advisory Board |
Sean Welton | - | 2014 | Member of Scientific Advisory Board |
Suzana Nahum-Zilberberg | 52 | 2021 | Independent Director |
Eyal Gottlieb | - | 2023 | Member of Scientific Advisory Board |
Yael Margolin | 70 | 2023 | Independent Director |
Simcha Rock | 74 | 2013 | Independent Director |
Ido Agmon | 47 | 2016 | Independent Director |
Isaac Israel | 46 | 2012 | Director |
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