WESTON, Fla. - ZyVersa Therapeutics, Inc. (NASDAQ: ZVSA), a biopharmaceutical company focused on developing drugs for inflammatory and renal diseases, has released a white paper detailing the potential of its Inflammasome ASC Inhibitor IC 100 in treating various neurological diseases. The paper, grounded in preclinical research, suggests that IC 100 can cross the blood-brain barrier and may offer a new approach to controlling inflammation in conditions such as multiple sclerosis, Alzheimer's disease, and traumatic brain injury.
The white paper, authored by Drs. Robert W. Keane and Juan Pablo de Rivero Vaccari of the University of Miami Miller School of Medicine, presents evidence that IC 100 targets multiple inflammasome pathways, which are believed to play a role in the development and progression of many neurological disorders. By inhibiting the release of ASC specks, IC 100 could potentially reduce the damaging inflammation that contributes to these diseases.
IC 100 is described as a novel humanized IgG4 monoclonal antibody that binds to the ASC component of inflammasomes, preventing the formation and activation of the inflammatory molecule IL-1β. The drug's ability to attenuate the inflammatory and adaptive immune response positions it as a promising candidate for further clinical development.
ZyVersa is nearing the completion of its preclinical program for IC 100 and anticipates filing an Investigational New Drug (IND) application in the fourth quarter of 2024. If approved, the company plans to initiate a phase 1 clinical trial in early 2025.
Stephen C. Glover, Co-founder, Chairman, CEO, and President of ZyVersa, expressed optimism about IC 100's potential impact on the lives of millions affected by neurological diseases. However, it is important to note that these statements are forward-looking and actual results may vary as the research progresses.
The white paper is part of ZyVersa's broader therapeutic development pipeline, which also includes drugs targeting renal diseases. The company's approach leverages proprietary technologies to create first-in-class drugs aimed at addressing significant unmet medical needs.
This report is based on a press release statement from ZyVersa Therapeutics, and it does not constitute an offer to sell or a solicitation of an offer to buy any securities.
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