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Valerio Therapeutics Société anonyme, a clinical-stage biotechnology company, designs and develops novel and first-in-class DNA-decoy therapies targeting proteins in tumors and inflammatory disease processes. The company develops AsiDNA, which is in phase 1b/2 trial in combination with the PARP inhibitor Olaparib to evaluate safety in patients with epithelial ovarian cancer, breast cancer, and metastatic castration-resistant prostate cancer; Revocan phase 1b/2 trial to evaluate the addition of AsiDNA to combat PARP inhibitor resistance in second-line maintenance treatment of recurrent ovarian cancer; and phase 1b/2 trial evaluating AsiDNA in combination with radiotherapy in recurrent highgrade glioma in children. It also develops VIO-01, a Pan-DDR DNA decoy targeting multiple proteins and repair pathways in preclinical development; and PlatON, a chemistry platform for building new molecules, which includes OX400, a decoy DNA platform. It has collaboration agreement with Gustave Roussy to conduct clinical trial of AsiDNA for the treatment of recurrent ovarian cancer. The company was formerly known as Onxeo SA and changed its name to Valerio Therapeutics Société anonyme in June 2023. Valerio Therapeutics Société anonyme was founded in 1997 and is headquartered in Paris, France.
Name | Age | Since | Title |
---|---|---|---|
Nicolas Trebouta | 61 | 2011 | Representative Director |
Julien Miara | 41 | 2020 | Director |
Ruth Plummer | - | 2021 | Member of Scientific Advisory Committee |
Shefali Agarwal | 51 | 2021 | President, CEO & Chairwoman |
Robert L. Coleman | 63 | 2021 | Independent Director |
Khalil Barrage | 59 | 2022 | Representative Director |
Gilles Favre | - | 2021 | Member of Scientific Advisory Committee |
Bryan Giraudo | 49 | 2021 | Independent Director |
Lorenzo Galluzzi | - | 2021 | Member of Scientific Advisory Committee |
Gilbert Chu | - | 2021 | Member of Scientific Advisory Committee |
Caroline Robert | - | 2021 | Member of Scientific Advisory Committee |
Jacques Mallet | 64 | 2021 | Independent Director |
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