BofA bullish on Immatics stock despite need for further dose optimization

Investing.com  |  Editor Emilio Ghigini

Published Nov 19, 2024 02:12

BofA bullish on Immatics stock despite need for further dose optimization

On Monday, BofA Securities adjusted its outlook on Immatics (NASDAQ:IMTX) stock, a clinical-stage biopharmaceutical company, by reducing the price target to $15 from the previous $16. Despite the decrease, the firm maintains a Buy rating.

The revision follows Immatics' third-quarter earnings for 2024, which revealed the first clinical data for IMA402, its TCR bispecific targeting PRAME, and provided updated timelines for the company's various therapies.

The analyst from BofA Securities noted that Immatics' shares were relatively stable, showing a slight 1% decrease in response to the earnings report, compared to a 0.4% dip in the NASDAQ Biotechnology Index.

The initial safety data for IMA402 appeared positive, with promising signs of response at higher doses. However, the analyst emphasized that further follow-up and dose optimization are necessary to mitigate risks.

The early clinical data for IMA402, along with recent advancements in IMA203, another therapy in development, have increased confidence in Immatics' TCR (T-cell receptor) approach. This is seen as a positive sign as the company anticipates additional updates in the following year.

Following a public offering in October 2024, Immatics is expected to have a cash runway extending into the second half of 2027, which should cover forthcoming pipeline readouts for all its assets.

The analyst's decision to reiterate the Buy rating but lower the price objective to $15 is attributed to a reduced cash balance and updated projections for revenue and expenses based on current trends.

In other recent news, Immatics, a clinical-stage biopharmaceutical company, has been the focus of several analyst evaluations. Piper Sandler recently gave Immatics an Overweight rating, setting a bullish price target of $19.00.

This optimistic outlook is anchored in the company's PRAME-targeting portfolio and IMA203, a leading cell therapy candidate for post-PD-1 melanoma. Piper Sandler also sees potential in IMA203CD8 for ovarian, endometrial, and lung cancers.

In addition, Mizuho (NYSE:MFG) maintained its Outperform rating for Immatics with a steady price target of $16.00. The affirmation followed the presentation of updated Phase 1 data at the European Society for Medical (TASE:PMCN) Oncology and the return of the IMA401 program from partner Bristol Myers (NYSE:BMY) Squibb.

The Phase 1 data for the therapeutic candidate, IMA401, showed a disease control rate of 55%, which Mizuho considers a promising indicator of efficacy for TCR-based therapies.

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Finally, Immatics has appointed Dr. Alise Reicin to its Board of Directors, adding valuable clinical and strategic expertise to the company as it advances its T cell-redirecting cancer immunotherapies. These recent developments reflect the ongoing progress and potential of Immatics in the biopharmaceutical sector.

InvestingPro Insights

Recent InvestingPro data and tips provide additional context to Immatics' (NASDAQ:IMTX) current financial situation and market performance, complementing BofA Securities' analysis. The company's market capitalization stands at $933.36 million, reflecting its position as a mid-cap biopharmaceutical firm.

InvestingPro Tips highlight that Immatics holds more cash than debt on its balance sheet, which aligns with the analyst's note on the company's cash runway extending into 2027. This strong liquidity position is further supported by the fact that Immatics' liquid assets exceed its short-term obligations, providing financial flexibility for its ongoing clinical trials and pipeline development.

However, investors should note that Immatics is not currently profitable, with a negative gross profit margin of -87.72% in the last twelve months as of Q2 2024. This is consistent with the company's status as a clinical-stage biopharmaceutical firm investing heavily in research and development. The stock's recent performance has been challenging, with a 17.31% decline over the past month and a 29.02% drop over the last three months, possibly reflecting market reactions to clinical data and financial results.

Interestingly, two analysts have revised their earnings upwards for the upcoming period, suggesting some optimism about Immatics' near-term prospects. The stock is currently trading near its 52-week low, with a price that is 56.79% of its 52-week high, potentially presenting a value opportunity for investors who share BofA Securities' positive long-term outlook.

For readers interested in a more comprehensive analysis, InvestingPro offers 11 additional tips for Immatics, providing a deeper understanding of the company's financial health and market position.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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